Challenge & Solution
AmyletiX is a new way to incorporate insoluble materials in water-based systems. It uses Guest/Host chemistry to disperse insoluble materials, not emulsify them. The helical host captures and hides insoluble guests in water. It lets you incorporate difficult active molecules in water-based systems, such as hydrophobic actives and oils. Topical ointments with a water base and hydrophobic actives are far more stable than emulsions of the same ingredients. Makes a molecular dispersion rather than an emulsion for greater stability. Better bioavailability and skin penetration.
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AmyletiX Technology is a new approach to making water-based and oil-in-water emulsions. It is a technology that uses guest/host chemistry to disperse insoluble materials. The helical host captures and hides insoluble guests in water. Lets you incorporate difficult active molecules in water based systems. Topical ointments with a water base and hydrophobic actives. Makes a molecular dispersion rather than an emulsion for greater stability. Better bio-availability and skin penetration.
In the world of cosmetics and personal care products, there are two main challenges:
- Difficult active ingredients or molecules, for example, retinoids that are not soluble in water.
- Insoluble actives that cannot be incorporated into a water-based system due to their lack of solubility in oil or other non-aqueous phases.
Our AmyletiX and AmphyletiX Technology solve both problems at once by using the unique chemistry of our hydrophilic and/or amphiphilic host molecule — one that is both lipophilic (oil loving) and hydrophilic (water-attracting). This combination allows us to encapsulate insoluble ingredients into a stable, self-assembled host structure that is resistant to aggregation and precipitation in aqueous solutions. The result is an emulsion-free molecular dispersion rather than an emulsion — with all its attendant stability problems.
AmyletiX Technology is a solution for the problems of molecular dispersion, hydrophobic actives and skin penetration.
AmyletiX uses guest/host chemistry to disperse insoluble materials in water. The helical host captures and hides insoluble guests in water. This results in a molecular dispersion rather than an emulsion for greater stability.